As you may already know, these are the most common symptoms experienced with Roaccutane. The drug aims to stop sebum secretion completely and thus, as a result, this will cause the skin to be less moisturised. Drying of the skin occurs and this leads to the formation of little cracks which are most prominent in the mucous membrane areas ( such as the lips and nasal passages).
The best thing to do is to apply a hypoallergenic aqueous based moisturiser to the face and use vaseline for the lips (or any other kind of lip balm). That will hopefully alleviate the symptoms you are experiencing.
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